The choice of resynchronization therapy between with (CRT-D) and without (CRT-P) a defibrillator remains a contentious issue. Cause-of-death analysis among CRT-P, compared with CRT-D, patients could help evaluate the extent to which CRT-P patients would have additionally benefited from a defibrillator in a daily clinical practice.A total of 1705 consecutive patients implanted with a CRT (CRT-P: 535 and CRT-D: 1170) between 2008 and 2010 were enrolled in CeRtiTuDe, a multicentric prospective follow-up cohort study, with specific adjudication for causes of death at 2 years. Patients with CRT-P compared with CRT-D were older (P < 0.0001), less often male (P < 0.0001), more symptomatic (P = 0.0005), with less coronary artery disease (P = 0.003), wider QRS (P = 0.002), more atrial fibrillation (P < 0.0001), and more co-morbidities (P = 0.04). At 2-year follow-up, the annual overall mortality rate was 83.80 [95

作者：Eloi, Marijon；Christophe, Leclercq；Kumar, Narayanan；Serge, Boveda；Didier, Klug；Jonathan, Lacaze-Gadonneix；Pascal, Defaye；Sophie, Jacob；Olivier, Piot；Jean-Claude, Deharo；Marie-Cecile, Perier；Genevieve, Mulak；Jean-Sylvain, Hermida；Paul, Milliez；Daniel, Gras；Olivier, Cesari；Fran?oise, Hidden-Lucet；Frederic, Anselme；Philippe, Chevalier；Philippe, Maury；Nicolas, Sadoul；Pierre, Bordachar；Serge, Cazeau；Michel, Chauvin；Jean-Philippe, Empana；Xavier, Jouven；Jean-Claude, Daubert；Jean-Yves, Le Heuzey

来源：European heart journal 2015 年 36卷 41期