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To evaluate the feasibility of non-invasive vascular real-time elastography imaging (RTE) in visualizing the composition of rabbit carotid atherosclerotic plaque as determined by histopathology, a rabbit model of accelerated carotid atherosclerosis was used. Thirty rabbits were randomly divided into two groups of 15 rabbits each. The first group was fed a cholesterol-rich diet and received balloon-induced injury the left common carotid artery endothelium, whereas the second group only received a cholesterol-rich diet. The rabbits were all examined in vivo with HITACHI non-invasive vascular real-time elastography (Hi-RTE) at baseline and 12 wk, and results from the elastography were compared with American Heart Association histologic classifications. Hi-RTE and the American Heart Association histologic classifications had good agreement, with weighted Cohen's kappa (95

作者:ZhenZhen, Wang;NaNa, Liu;LiFeng, Zhang;XiaoYing, Li;XueSong, Han;YanQing, Peng;MeiZheng, Dang;LiTao, Sun;JiaWei, Tian

来源:Ultrasound in medicine & biology 2016 年 42卷 1期

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作者:
ZhenZhen, Wang;NaNa, Liu;LiFeng, Zhang;XiaoYing, Li;XueSong, Han;YanQing, Peng;MeiZheng, Dang;LiTao, Sun;JiaWei, Tian
来源:
Ultrasound in medicine & biology 2016 年 42卷 1期
标签:
Atherosclerosis Histology Plaques Rabbit carotid artery Real-time elastography Ultrasound
To evaluate the feasibility of non-invasive vascular real-time elastography imaging (RTE) in visualizing the composition of rabbit carotid atherosclerotic plaque as determined by histopathology, a rabbit model of accelerated carotid atherosclerosis was used. Thirty rabbits were randomly divided into two groups of 15 rabbits each. The first group was fed a cholesterol-rich diet and received balloon-induced injury the left common carotid artery endothelium, whereas the second group only received a cholesterol-rich diet. The rabbits were all examined in vivo with HITACHI non-invasive vascular real-time elastography (Hi-RTE) at baseline and 12 wk, and results from the elastography were compared with American Heart Association histologic classifications. Hi-RTE and the American Heart Association histologic classifications had good agreement, with weighted Cohen's kappa (95