An 11-year-old boy was diagnosed with chronic recurrent multifocal osteomyelitis (CRMO) and presented with right sacro-femoral and occipital lesions. Initially, a tumor was suspected. However, the bone biopsy showed osteomyelitis with a negative bacterial culture. Bone scintigraphy revealed inflammatory changes on multiple bone lesions. The slight elevation in inflammatory markers such as C-reactive protein was of little clinical value. He was diagnosed with CRMO by sacral biopsy, and the clinical course progressed, with the presence of a new occipital lesion observed after the 1-year follow-up. The administration of non-steroidal anti-inflammatory drugs successfully improved his clinical symptoms. The presence of a skull lesion in the occipital bone of a pediatric patient with CRMO has not been previously reported.

作者：Toru, Watanabe；Hiroyuki, Ono；Yoshitaka, Morimoto；Yoshiro, Otsuki；Masami, Shirai；Akira, Endoh；Masaaki, Naito；Yoshiya, Inoue；Teruaki, Hongo

来源：Nagoya journal of medical science 2015 年 77卷 3期