In the clinical setting, bleeding is a common manifestation of acute promyelocytic leukemia (APL), whereas thrombosis is relatively rare, especially as an initial symptom. Here, we report an unusual case of APL with acute myocardial infarction as the first manifestation and cerebral infarction as the relapse manifestation in a healthy young woman. This unique case emphasizes that a thrombotic event could be the first manifestation of an underlying hematological disorder such as APL and could also be a sign of relapse. Rapid detection of the underlying disorder and the timely use of anticoagulation therapy and ATRA are crucial for preventing further deterioration of the disease and saving the patient's life.

作者：Ying, Li；Shanshan, Suo；Liping, Mao；Lei, Wang；Chunmei, Yang；Weilai, Xu；Yinjun, Lou；Wenyuan, Mai

来源：International journal of clinical and experimental medicine 2015 年 8卷 8期