Motor complications may become major challenges in the management of patients with Parkinson's disease. In this study, we sought to determine the incidence, risk factors, evolution, and treatment of motor fluctuations and dyskinesias in a population-representative, incident Parkinson's disease cohort.In this prospective population-based 5-year longitudinal study, we followed 189 incident and initially drug-naïve Parkinson's disease patients biannually for detailed examination of dyskinesias and motor fluctuations as defined by the Unified Parkinson's disease Rating Scale. We performed Kaplan-Meier survival and Cox regression analyses to assess cumulative incidence and risk factors of these motor complications.The 5-year cumulative incidence of motor complications was 52.4

作者：Anders, Bjornestad；Elin B, Forsaa；Kenn Freddy, Pedersen；Ole-Bjorn, Tysnes；Jan Petter, Larsen；Guido, Alves

来源：Parkinsonism & related disorders 2016 年 22卷