lonophore-based ion-selective optical nanosensors have been explored for a number of years. Voltage sensitive dyes (VSDs) have been introduced into this type of sensors only very recently, forming a new class of analytical tools. Here, K(+)-sensitive nanospheres incorporating a lipophilic VSD were successfully fabricated and characterized. The nanosensors were readily delivered into the social amoeba Dictyostelium discoideum in a non-invasive manner, forming a promising new platform for intracellular ion quantification and imaging.
作者:Xiaojiang, Xie;Agustín, Gutiérrez;Valentin, Trofimov;Istvan, Szilagyi;Thierry, Soldati;Eric, Bakker
来源:Chimia 2015 年 69卷 4期