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To investigate whether eating disorders are associated with lower size at birth, symmetric growth restriction, and preterm birth; and whether pregnancy smoking explains the association between anorexia nervosa and fetal growth.Longitudinal population-based cohort study.Denmark.Women from the Danish National Birth Cohort (n = 83 826).Women with anorexia nervosa (n = 1609), bulimia nervosa (n = 1693) and both (anorexia + bulimia nervosa, n = 634) were compared with unexposed women (n = 76 724) (women with exposure data and singletons n = 80 660) using crude and adjusted linear and logistic regression models.Size at birth (birthweight, length, head and abdominal circumference and placental weight); gestational age; small- and large-for-gestational-age (SGA, LGA); ponderal index, abdominal/head circumference.Lifetime anorexia nervosa and lifetime anorexia + bulimia nervosa were prospectively associated with restricted fetal growth and higher odds of SGA [respectively, OR = 1.6 [95

作者:N, Micali;P, Stemann Larsen;K, Strandberg-Larsen;A-M, Nybo Andersen

来源:BJOG : an international journal of obstetrics and gynaecology 2016 年 123卷 8期

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作者:
N, Micali;P, Stemann Larsen;K, Strandberg-Larsen;A-M, Nybo Andersen
来源:
BJOG : an international journal of obstetrics and gynaecology 2016 年 123卷 8期
标签:
Anorexia nervosa bulimia nervosa eating disorders growth obstetric restriction
To investigate whether eating disorders are associated with lower size at birth, symmetric growth restriction, and preterm birth; and whether pregnancy smoking explains the association between anorexia nervosa and fetal growth.Longitudinal population-based cohort study.Denmark.Women from the Danish National Birth Cohort (n = 83 826).Women with anorexia nervosa (n = 1609), bulimia nervosa (n = 1693) and both (anorexia + bulimia nervosa, n = 634) were compared with unexposed women (n = 76 724) (women with exposure data and singletons n = 80 660) using crude and adjusted linear and logistic regression models.Size at birth (birthweight, length, head and abdominal circumference and placental weight); gestational age; small- and large-for-gestational-age (SGA, LGA); ponderal index, abdominal/head circumference.Lifetime anorexia nervosa and lifetime anorexia + bulimia nervosa were prospectively associated with restricted fetal growth and higher odds of SGA [respectively, OR = 1.6 [95