Published studies showed controversial findings about the relationship between glutathione S-transferase M1 (GSTM1) null genotype and clinical outcomes of patients with colorectal cancer. We performed a meta-analysis to quantitatively assess the association between GSTM1 null genotype and prognosis of patients with colorectal cancer. We systematically searched Pubmed, Embase, and Web of Science to identify prospective or retrospective cohort studies assessing the association of GSTM1 null genotype with overall survival (OS) or disease-free survival (DFS) in colorectal cancer. The hazard ratios (HRs) and 95 

作者：Shushan, Yan；Zengfang, Wang；Zengyan, Wang；Quanhong, Duan；Xiaochen, Wang；Jun, Li；Beicheng, Sun

来源：Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 年 37卷 8期