To investigate gastrointestinal complications associated with non-steroidal anti-inflammatory drug (NSAIDs) use in children.A retrospective, multicenter study was conducted between January 2005 and January 2013, with the participation of 8 Italian pediatric gastroenterology centers. We collected all the cases of patients who refer to emergency room for suspected gastrointestinal bleeding following NSAIDs consumption, and underwent endoscopic evaluation. Previous medical history, associated risk factors, symptoms and signs at presentation, diagnostic procedures, severity of bleeding and management of gastrointestinal bleeding were collected. In addition, data regarding type of drug used, indication, dose, duration of treatment and prescriber (physician or self-medication) were examined.Fifty-one patients, including 34 males, were enrolled (median age: 7.8 years). Ibuprofen was the most used NSAID [35/51 patients (68.6
作者:Sabrina, Cardile;Massimo, Martinelli;Arrigo, Barabino;Paolo, Gandullia;Salvatore, Oliva;Giovanni, Di Nardo;Luigi, Dall'Oglio;Francesca, Rea;Gian Luigi, de'Angelis;Barbara, Bizzarri;Graziella, Guariso;Enzo, Masci;Annamaria, Staiano;Erasmo, Miele;Claudio, Romano
来源:World journal of gastroenterology 2016 年 22卷 5期