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Cancer patients are at increased risk for venous thromboembolism (VTE).This monocenter cross-sectional study prospectively assessed the association between a history of ≥1 VTE episode and the presence of pulmonary hypertension (PH) among cancer patients presenting with pulmonary or cardiac symptoms.A consecutive series of 583 patients underwent a diagnostic work-up for heart and lung disease. PH was diagnosed if a patient's peak systolic pressure gradient across the tricuspid valve was ≥35 mmHg, as measured by echocardiography. Using multiple logistic regression analysis, the association between VTE and PH was assessed, following adjustments for age, the presence of severe airway obstruction, atrial fibrillation and left heart diseases.The prevalence values for PH (n = 90) and a history of VTE (n = 72) were 15.4 and 12.3 

作者:Siegfried, Wieshammer;Jens, Dreyhaupt;Dirk, Müller;Felix, Momm;Andreas, Jakob

来源:Thrombosis journal 2016 年 14卷

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作者:
Siegfried, Wieshammer;Jens, Dreyhaupt;Dirk, Müller;Felix, Momm;Andreas, Jakob
来源:
Thrombosis journal 2016 年 14卷
标签:
Cancer Heart disease Pulmonary hypertension Venous thromboembolism
Cancer patients are at increased risk for venous thromboembolism (VTE).This monocenter cross-sectional study prospectively assessed the association between a history of ≥1 VTE episode and the presence of pulmonary hypertension (PH) among cancer patients presenting with pulmonary or cardiac symptoms.A consecutive series of 583 patients underwent a diagnostic work-up for heart and lung disease. PH was diagnosed if a patient's peak systolic pressure gradient across the tricuspid valve was ≥35 mmHg, as measured by echocardiography. Using multiple logistic regression analysis, the association between VTE and PH was assessed, following adjustments for age, the presence of severe airway obstruction, atrial fibrillation and left heart diseases.The prevalence values for PH (n = 90) and a history of VTE (n = 72) were 15.4 and 12.3