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Abnormalities of fibroblast growth factor-23 (FGF-23) plasma levels predict adverse outcomes in patients with coronary artery disease. However, FGF-23 has a different behaviour in the presence of type 2 diabetes mellitus (T2D). We explored whether the presence of T2D affects the predictive power of FGF-23.In 704 patients with stable coronary artery disease, FGF-23, calcidiol, parathormone (PTH) and phosphate plasma levels were prospectively assessed. The primary outcome was the development of acute ischemic events (acute coronary syndrome, stroke or transient ischemic attack), heart failure or death.One hundred seventy-three (24.6

作者:José, Tu?ón;Beatriz, Fernández-Fernández;Rocío, Carda;Ana M, Pello;Carmen, Cristóbal;Nieves, Tarín;álvaro, Ace?a;María Luisa, González-Casaus;Ana, Huelmos;Joaquín, Alonso;óscar, Lorenzo;Emilio, González-Parra;Ignacio, Hernández-González;Ignacio, Mahíllo-Fernández;Lorenzo, López-Bescós;Jesús, Egido

来源:Diabetes/metabolism research and reviews 2016 年 32卷 7期

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作者:
José, Tu?ón;Beatriz, Fernández-Fernández;Rocío, Carda;Ana M, Pello;Carmen, Cristóbal;Nieves, Tarín;álvaro, Ace?a;María Luisa, González-Casaus;Ana, Huelmos;Joaquín, Alonso;óscar, Lorenzo;Emilio, González-Parra;Ignacio, Hernández-González;Ignacio, Mahíllo-Fernández;Lorenzo, López-Bescós;Jesús, Egido
来源:
Diabetes/metabolism research and reviews 2016 年 32卷 7期
标签:
coronary artery disease diabetes mellitus fibroblast growth factor-23 mineral metabolism vitamin D
Abnormalities of fibroblast growth factor-23 (FGF-23) plasma levels predict adverse outcomes in patients with coronary artery disease. However, FGF-23 has a different behaviour in the presence of type 2 diabetes mellitus (T2D). We explored whether the presence of T2D affects the predictive power of FGF-23.In 704 patients with stable coronary artery disease, FGF-23, calcidiol, parathormone (PTH) and phosphate plasma levels were prospectively assessed. The primary outcome was the development of acute ischemic events (acute coronary syndrome, stroke or transient ischemic attack), heart failure or death.One hundred seventy-three (24.6