Fertility preservation options are limited in prepubertal boys with cancer. Worldwide there has been growing interest in testicular tissue cryopreservation as a promising experimental strategy to address future infertility. We measured and compared parent, male cancer survivor and provider willingness to accept the risk of testicular biopsy among prepubertal boys with cancer, and identified reactions to disclosure practices.We conducted a multicenter study that included 153 parents of prepubertal boys with cancer, 77 male survivors of childhood cancer and 30 oncology providers. The threshold technique was used to measure subject relative willingness to accept risk of testicular biopsy under 4 different aspects of care, ie chance of infertility, complications from biopsy, development of technology to use tissue and tissue storage cost. A total of 47 in-depth interviews were conducted to identify reactions to disclosure practices.A total of 52 survivors (67

作者：Abha A, Gupta；Rachel M, Donen；Lillian, Sung；Katherine M, Boydell；Kirk C, Lo；Derek, Stephens；Sheila, Pritchard；Carol, Portwine；Anne Marie, Maloney；Armando J, Lorenzo

来源：The Journal of urology 2016 年 196卷 1期