The Vanderbilt Memory & Aging Project: Study Design and Baseline Cohort Overview.-临床诊疗知识库

The Vanderbilt Memory & Aging Project: Study Design and Baseline Cohort Overview.

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作者：

Angela L, Jefferson；Katherine A, Gifford；Lealani Mae Y, Acosta；Susan P, Bell；Manus J, Donahue；L Taylor, Davis；JoAnn, Gottlieb；Deepak K, Gupta；Timothy J, Hohman；Elizabeth M, Lane；David J, Libon；Lisa A, Mendes；Kevin, Niswender；Kimberly R, Pechman；Swati, Rane；Frederick L, Ruberg；Yan Ru, Su；Henrik, Zetterberg；Dandan, Liu

来源：

Journal of Alzheimer's disease : JAD 2016 年 52卷 2期

标签：

Alzheimer’s disease biomarkers brain MRI cardiac MRI mild cognitive impairment vascular risk factors

Vascular health factors frequently co-occur with Alzheimer's disease (AD). A better understanding of how systemic vascular and cerebrovascular health intersects with clinical and pathological AD may inform prevention and treatment opportunities.To establish the Vanderbilt Memory & Aging Project, a case-control longitudinal study investigating vascular health and brain aging, and describe baseline methodology and participant characteristics.From September 2012 to November 2014, 335 participants age 60- 92 were enrolled, including 168 individuals with mild cognitive impairment (MCI, 73±8 years, 41

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