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We present a human immunodeficiency virus-infected patient with severe decompensated hepatitis C virus-related cirrhosis awaiting liver transplantation (LT) who received a 24-week course of interferon/ribavirin-free antiviral treatment with sofosbuvir and daclatasvir on a compassionate basis. Rapid viral suppression was associated with progressive improvement of his liver function tests. The patient achieved a sustained virological response and concomitant clinical improvement, which prompted removal from the LT list 12 weeks after the end of treatment.

作者:J, Llaneras;L, Castells;B, Santos;M, Crespo;T, Puig;J I, Esteban;R, Esteban

来源:Transplant infectious disease : an official journal of the Transplantation Society 2016 年 18卷 3期

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作者:
J, Llaneras;L, Castells;B, Santos;M, Crespo;T, Puig;J I, Esteban;R, Esteban
来源:
Transplant infectious disease : an official journal of the Transplantation Society 2016 年 18卷 3期
标签:
daclatasvir hepatitis C virus human immunodeficiency virus sofosbuvir transplant
We present a human immunodeficiency virus-infected patient with severe decompensated hepatitis C virus-related cirrhosis awaiting liver transplantation (LT) who received a 24-week course of interferon/ribavirin-free antiviral treatment with sofosbuvir and daclatasvir on a compassionate basis. Rapid viral suppression was associated with progressive improvement of his liver function tests. The patient achieved a sustained virological response and concomitant clinical improvement, which prompted removal from the LT list 12 weeks after the end of treatment.