Guidelines for stroke prevention recommend development of sex-specific stroke risk scores. Incorporating sex in Clinical Prediction Models (CPMs) may support sex-specific clinical decision making. To better understand their potential to guide sex-specific care, we conducted a field synopsis of the role of sex in stroke-related CPMs.We identified stroke-related CPMs in the Tufts Predictive Analytics and Comparative Effectiveness CPM Database, a systematic summary of cardiovascular CPMs published from January 1990 to May 2012. We report the proportion of models including the effect of sex on stroke incidence or prognosis, summarize the directionality of the predictive effects of sex, and explore factors influencing the inclusion of sex. Of 92 stroke-related CPMs, 30 (33

作者：Jessica K, Paulus；Lana Y H, Lai；Christine, Lundquist；Ali, Daneshmand；Hannah, Buettner；Jennifer S, Lutz；Gowri, Raman；Benjamin S, Wessler；David M, Kent

来源：Journal of the American Heart Association 2016 年 5卷 5期