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Numerous studies have stated that Ki-67 is a good prognostic marker in oral squamous cell carcinoma (OSCC). However, some researchers believe the contrary. To address this controversy, we performed a systematic literature retrieval to estimate the prognostic significance of Ki-67 expression in patients with OSCC.Databases covering Pubmed, Ovid, Web of Science, Embase and the Cochrane library were searched regardless of publication year. Overall survival (OS), local recurrence (LR) and disease-free survival (DFS) were the main outcome measures. Relative risks (RRs) and its 95

作者:Shang, Xie;Ying, Liu;Xue, Qiao;Rui-Xi, Hua;Kan, Wang;Xiao-Feng, Shan;Zhi-Gang, Cai

来源:Journal of Cancer 2016 年 7卷 7期

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作者:
Shang, Xie;Ying, Liu;Xue, Qiao;Rui-Xi, Hua;Kan, Wang;Xiao-Feng, Shan;Zhi-Gang, Cai
来源:
Journal of Cancer 2016 年 7卷 7期
标签:
Ki-67 Meta-analysis. OSCC Oral squamous cell carcinoma Prognosis Survival
Numerous studies have stated that Ki-67 is a good prognostic marker in oral squamous cell carcinoma (OSCC). However, some researchers believe the contrary. To address this controversy, we performed a systematic literature retrieval to estimate the prognostic significance of Ki-67 expression in patients with OSCC.Databases covering Pubmed, Ovid, Web of Science, Embase and the Cochrane library were searched regardless of publication year. Overall survival (OS), local recurrence (LR) and disease-free survival (DFS) were the main outcome measures. Relative risks (RRs) and its 95