To elucidate and compare benefit-risk preferences among Korean patients and physicians concerning cyclooxygenase-2 (Cox-2) inhibitor treatments for arthritis.Subjects included 100 patients with arthritis and 60 board-certified orthopedic surgeon physicians in South Korea. Through a systematic review of the literature, beneficial attributes of using Cox-2 inhibitors were defined as a decrease in the Western Ontario and McMaster Universities Arthritis Index for pain score and improvement in physical function. Likewise, risk attributes included upper gastrointestinal (GI) complications and cardiovascular (CV) adverse events. Discrete choice experiments were used to determine preferences for these four attributes among Korean patients and physicians. Relative importance and maximum acceptable risk for improving beneficial attributes were assessed by analyzing the results of the discrete choice experiment by using a conditional logit model.Patients ranked the relative importance of benefit-risk attributes as follows: pain reduction (35.2

作者：Ji-Hye, Byun；Sun-Hong, Kwon；Ji-Eun, Lee；Ji-Eun, Cheon；Eun-Jin, Jang；Eui-Kyung, Lee

来源：Patient preference and adherence 2016 年 10卷