Patient and health system determinants of outcomes following pancreatic cancer resection, particularly the relative importance of hospital and surgeon volume, are unclear. Our objective was to identify patient, tumour and health service factors related to mortality and survival amongst a cohort of patients who underwent completed resection for pancreatic cancer.Eligible patients were diagnosed with pancreatic adenocarcinoma between July 2009 and June 2011 and had a completed resection performed in Queensland or New South Wales, Australia, with either tumour-free (R0) or microscopically involved margins (R1) (n = 270). Associations were examined using logistic regression (for binary outcomes) and Cox proportional hazards or stratified Cox models (for time-to-event outcomes).Patients treated by surgeons who performed <4 resections/year were more likely to die from a surgical complication (versus ≥4 resections/year, P = 0.04), had higher 1-year mortality (P = 0.03), and worse overall survival up to 1.5 years after surgery (adjusted hazard ratio 1.58, 95
作者:Mary A, Waterhouse;Elizabeth A, Burmeister;Dianne L, O'Connell;Emma L, Ballard;Susan J, Jordan;Neil D, Merrett;David, Goldstein;David, Wyld;Monika, Janda;Vanessa L, Beesley;Madeleine E, Payne;Helen M, Gooden;Rachel E, Neale
来源:Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2016 年 20卷 8期