The pro-atherosclerotic nature of vitamin D deficiency has been shown to increase cardiovascular events. We further emphasized and evaluated the severity of coronary artery disease (CAD) with varying levels of vitamin D in relation to age, gender, ethnicity and baseline confounders.A retrospective, single-center study of 9,399 patients admitted between 2005 and 2014 for chest pain who underwent coronary angiography. Patients without a vitamin D level, measured as 25-dihydroxyvitamin D (25[OH]D) were excluded from our study. 25(OH)D deficiency and insufficiency were defined by having serum concentration levels of less than 20 ng/ml and 20 to 29.9 ng/ml, respectively, while normal levels were defined as greater than or equal to 30 ng/ml. We assessed levels of 25(OH)D and extent of coronary disease with coronary angiography as obstructive CAD (left main stenosis of ≥50

作者：Robert, Sogomonian；Hassan, Alkhawam；JoshPaul, Jolly；Neil, Vyas；Sumair, Ahmad；Emma, Moradoghli Haftevani；Ahmed, Al-Khazraji；Dennis, Finkielstein；Timothy J, Vittorio

来源：Expert review of cardiovascular therapy 2016 年 14卷 8期