Transcriptome sequences spanning key developmental states as a resource for the study of the cestode Schistocephalus solidus, a threespine stickleback parasite.-临床诊疗知识库

Transcriptome sequences spanning key developmental states as a resource for the study of the cestode Schistocephalus solidus, a threespine stickleback parasite.

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作者：

Fran?ois Olivier, Hébert；Stephan, Grambauer；Iain, Barber；Christian R, Landry；Nadia, Aubin-Horth

来源：

GigaScience 2016 年 5卷

标签：

Cestode Flatworm Gasterosteus aculeatus Parasite RNA-seq Schistocephalus solidus Threespine stickleback Transcriptome de novo assembly

Schistocephalus solidus is a well-established model organism for studying the complex life cycle of cestodes and the mechanisms underlying host-parasite interactions. However, very few large-scale genetic resources for this species are available. We have sequenced and de novo-assembled the transcriptome of S. solidus using tissues from whole worms at three key developmental states - non-infective plerocercoid, infective plerocercoid and adult plerocercoid - to provide a resource for studying the evolution of complex life cycles and, more specifically, how parasites modulate their interactions with their hosts during development.The de novo transcriptome assembly reconstructed the coding sequence of 10,285 high-confidence unigenes from which 24,765 non-redundant transcripts were derived. 7,920 (77

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