To investigate the effect of age of myopia onset on the severity of myopia later in life among myopic children.In this prospective study, school children aged 7-9 years from the Singapore Cohort Of the Risk factors for Myopia (SCORM) were followed up till 11 years (n = 928). Age of myopia onset was defined either through questionnaire at baseline (age 7-9 years) or subsequent annual follow-up visits. Age of onset of myopia was a surrogate indicator of duration of myopia progression till age 11 years. Cycloplegic refraction and axial length were measured at every annual eye examination. High myopia was defined as spherical equivalent of ≤-5.0 D. A questionnaire determined the other risk factors.In multivariable regression models, younger age of myopia onset (per year decrease) or longer duration of myopia progression was associated with high myopia (odds ratio (OR) = 2.86; 95

作者：Sharon Y L, Chua；Charumathi, Sabanayagam；Yin-Bun, Cheung；Audrey, Chia；Robert K, Valenzuela；Donald, Tan；Tien-Yin, Wong；Ching-Yu, Cheng；Seang-Mei, Saw

来源：Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) 2016 年 36卷 4期