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Numerous case-control studies have been performed to investigate the association between three cyclooxygenase-2 (COX-2) polymorphisms (rs20417 (-765G > C), rs689466 (-1195G > A), and rs5275 (8473 T > C)) and the risk of head and neck squamous cell carcinoma (HNSCC). However, the results were inconsistent. Therefore, we conducted this meta-analysis to investigate the association.We searched in PubMed, Embase, and Web of Science up to January 20, 2015 (last updated on May 12, 2016). Two independent reviewers extracted the data. Odds ratios (ORs) with their 95 

作者:Wei-Dong, Leng;Xiu-Jie, Wen;Joey S W, Kwong;Wei, Huang;Jian-Gang, Chen;Xian-Tao, Zeng

来源:BMC cancer 2016 年 16卷

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作者:
Wei-Dong, Leng;Xiu-Jie, Wen;Joey S W, Kwong;Wei, Huang;Jian-Gang, Chen;Xian-Tao, Zeng
来源:
BMC cancer 2016 年 16卷
标签:
COX-2 rs20417 COX-2 rs5275 COX-2 rs689466 Head and neck squamous cell carcinoma Meta-analysis Polymorphism
Numerous case-control studies have been performed to investigate the association between three cyclooxygenase-2 (COX-2) polymorphisms (rs20417 (-765G > C), rs689466 (-1195G > A), and rs5275 (8473 T > C)) and the risk of head and neck squamous cell carcinoma (HNSCC). However, the results were inconsistent. Therefore, we conducted this meta-analysis to investigate the association.We searched in PubMed, Embase, and Web of Science up to January 20, 2015 (last updated on May 12, 2016). Two independent reviewers extracted the data. Odds ratios (ORs) with their 95