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The objectives of this study were to determine the impact of diabetes mellitus (DM) on antituberculosis drug resistance in new cases of tuberculosis (TB). A case-control study was conducted on all newly diagnosed pulmonary TB adult patients with DM as cases and without DM as controls who were hospitalised from May 2013 to October 2013 in Iran. A molecular resistance test for rapid detection of resistance to isoniazid and rifampicin was done. Multivariate analysis was performed to determine the impact of DM on any anti-TB drug resistance. In total, 62 TB cases with DM and 64 TB cases without DM were included. TB cases with DM were more likely to be older (59 years vs. 43 years; P=0.001). Two TB-DM patients had multidrug-resistant TB (MDR-TB) (3.2

作者:Parvaneh, Baghaei;Payam, Tabarsi;Pedram, Javanmard;Parissa, Farnia;Majid, Marjani;Afshin, Moniri;Mohammad Reza, Masjedi;Ali Akbar, Velayati

来源:Journal of global antimicrobial resistance 2016 年 4卷

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作者:
Parvaneh, Baghaei;Payam, Tabarsi;Pedram, Javanmard;Parissa, Farnia;Majid, Marjani;Afshin, Moniri;Mohammad Reza, Masjedi;Ali Akbar, Velayati
来源:
Journal of global antimicrobial resistance 2016 年 4卷
标签:
Anti-TB drugs Antituberculosis drug resistance Diabetes mellitus MDR-TB Tuberculosis
The objectives of this study were to determine the impact of diabetes mellitus (DM) on antituberculosis drug resistance in new cases of tuberculosis (TB). A case-control study was conducted on all newly diagnosed pulmonary TB adult patients with DM as cases and without DM as controls who were hospitalised from May 2013 to October 2013 in Iran. A molecular resistance test for rapid detection of resistance to isoniazid and rifampicin was done. Multivariate analysis was performed to determine the impact of DM on any anti-TB drug resistance. In total, 62 TB cases with DM and 64 TB cases without DM were included. TB cases with DM were more likely to be older (59 years vs. 43 years; P=0.001). Two TB-DM patients had multidrug-resistant TB (MDR-TB) (3.2