To retrospectively validate the American Society for Reproductive Medicine (ASRM) guidelines/recommendations concerning endocrine evaluation in a cohort of white European men presenting for couple's infertility.Retrospective study.Academic reproductive medicine outpatient clinic.Cohort of 1,056 consecutive infertile men (noninterracial infertile couples).Testicular volume was assessed with a Prader orchidometer. Serum hormones were measured (8-10 a.m.) in all cases. Hypogonadism was defined as total T < 3 ng/mL, according to the Endocrine Society definition. Semen analysis values were assessed based on the 2010 World Health Organisation reference criteria.ASRM indications for endocrine assessment in infertile men (sperm concentration <10 million/mL, impaired sexual function, and other clinical findings suggesting a specific endocrinopathy) were used to predict hypogonadism in our cohort. Moreover, a clinically user-friendly three-item nomogram was developed to predict hypogonadism and was compared to the ASRM guidelines assessment.Biochemical hypogonadism was diagnosed in 156 (14.8

作者：Eugenio, Ventimiglia；Paolo, Capogrosso；Luca, Boeri；Silvia, Ippolito；Roberta, Scano；Marco, Moschini；Giorgio, Gandaglia；Enrico, Papaleo；Francesco, Montorsi；Andrea, Salonia

来源：Fertility and sterility 2016 年 106卷 5期