A functional cancer theranostic nanoplatform is developed, specifically tailored toward the optoacoustic modality by combining gold nanorods with DNA nanostructures (D-AuNR). DNA origami is used as an efficient delivery vehicle owing to its prominent tumor-targeting property. The D-AuNR hybrids display an enhanced tumor diagnostic sensitivity by improved optoacoustic imaging and excellent photothermal therapeutic properties in vivo.
作者:Yang, Du;Qiao, Jiang;Nicolas, Beziere;Linlin, Song;Qian, Zhang;Dong, Peng;Chongwei, Chi;Xin, Yang;Hongbo, Guo;Ga?l, Diot;Vasilis, Ntziachristos;Baoquan, Ding;Jie, Tian
来源:Advanced materials (Deerfield Beach, Fla.) 2016 年 28卷 45期