The aim of this study is to compare calculated free testosterone (cFT) and total testosterone (T) in predicting late-onset hypogonadism (LOH) in middle-aged and elderly males.We surveyed a random sample of 608 males between the ages of 45 and 87 years from Shanghai, China. The Aging Male Symptoms (AMS) questionnaire and the Androgen Deficiency in Aging Male (ADAM) questionnaire were completed by the subjects. Testosterone (T), sex hormone-binding globulin (SHBG), albumin, and other blood biochemical indexes were measured in 332 males. The corresponding cFT was obtained using the Vermeulen formula and the correlations between T and cFT were analyzed by SPSS statistical software.Among the 332 males who underwent biochemical evaluation, 289 males (87.0

作者：Zhangshun, Liu；Jie, Liu；Xiaohong, Shi；Lihong, Wang；Yan, Yang；Minfang, Tao；Qiang, Fu

来源：Journal of clinical laboratory analysis 2016 年