Effects of diet composition on weight loss, metabolic factors and biomarkers in a 1-year weight loss intervention in obese women examined by baseline insulin resistance status.-临床诊疗知识库

Effects of diet composition on weight loss, metabolic factors and biomarkers in a 1-year weight loss intervention in obese women examined by baseline insulin resistance status.

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作者：

Cheryl L, Rock；Shirley W, Flatt；Bilge, Pakiz；Elizabeth L, Quintana；Dennis D, Heath；Brinda K, Rana；Loki, Natarajan

来源：

Metabolism: clinical and experimental 2016 年 65卷 11期

标签：

Breast cancer Diet composition Insulin resistance Walnuts Weight loss

Obesity is a risk factor for postmenopausal breast cancer incidence and premenopausal and postmenopausal breast cancer mortality, which may be explained by several metabolic and hormonal factors (sex hormones, insulin resistance, and inflammation) that are biologically related. Differential effects of dietary composition on weight loss and these metabolic factors may occur in insulin-sensitive vs. insulin-resistant obese women.To examine the effect of diet composition on weight loss and metabolic, hormonal and inflammatory factors in overweight/obese women stratified by insulin resistance status in a 1-year weight loss intervention.Nondiabetic women who were overweight/obese (n=245) were randomly assigned to a lower fat (20

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