The prevalence of non-alcoholic fatty liver disease (NAFLD) and Crohn's disease (CD) is increasing. The aim of our study was to evaluate the prevalence of NAFLD in patients with CD, as well as to investigate the effect of NAFLD on the disease course of CD.Our retrospective cohort study included 303 patients who underwent abdominal ultrasound for CD and NAFLD diagnosis at our center between November 2008 and October 2014. Serum C-reactive protein (CRP) level and rate of remission, defined by a score <150 on the Crohn's Disease Activity Index, were compared between CD patients with and without NAFLD, using multivariate logistic regression. The effect of NAFLD on the surgery-free interval was evaluated using Cox proportional hazards models, adjusted for potential demographic confounders.Non-alcoholic fatty liver disease was diagnosed in 66 (21.8
作者:Shintaro, Sagami;Yoshitaka, Ueno;Shinji, Tanaka;Akira, Fujita;Ryohei, Hayashi;Shiro, Oka;Hideyuki, Hyogo;Kazuaki, Chayama
来源:Hepatology research : the official journal of the Japan Society of Hepatology 2016 年