Sufficiently detailed abstracts of randomized controlled trials (RCTs) are important, because readers often base their assessment of a trial solely on information in the abstract. We aimed at comparing reporting quality of RCTs in HIV/AIDS medicine before and after the publication of the 2008 CONSORT extension for abstracts and to investigate factors associated with better reporting quality.We searched PubMed/Medline for HIV/AIDS RCTs published between 2006-07 (Pre-CONSORT) and 2014-15 (Post-CONSORT) in 40 leading general medicine and infectious diseases journals. Two investigators extracted data and scored abstracts. The primary outcome was the adjusted mean number of items reported among the 17 required. Proportions of abstracts reporting each of 17 items were considered as secondary outcome. The adjustment was done for journal field, CONSORT endorsement, abstract format, type of intervention, journal impact factor and authorship. This study received no funding.The adjusted mean number of reported items was 7.2 (95
作者:Jean Joel R, Bigna;Jean Jacques N, Noubiap;Serra Lem, Asangbeh;Lewis N, Um;Paule Sandra D, Sime;Elvis, Temfack;Mathurin Cyrille, Tejiokem
来源:BMC medical research methodology 2016 年 16卷 1期