To investigate the reliability of a new in-house automatic algorithm for calculating the Magnetic Resonance Parkinsonism Index (MRPI), in a large multicentre study population of patients affected by progressive supranuclear palsy (PSP) or Parkinson's disease (PD), and healthy controls (HC), and to compare the diagnostic accuracy of the automatic and manual MRPI values.The study included 88 PSP patients, 234 PD patients and 117 controls. MRI was performed using both 3T and 1.5T scanners. Automatic and manual MRPI values were evaluated, and accuracy of both methods in distinguishing PSP from PD and controls was calculated.No statistical differences were found between automated and manual MRPI values in all groups. The automatic MRPI values differentiated PSP from PD with an accuracy of 95 

作者：Salvatore, Nigro；Gennarina, Arabia；Angelo, Antonini；Luca, Weis；Andrea, Marcante；Alessandro, Tessitore；Mario, Cirillo；Gioacchino, Tedeschi；Stefano, Zanigni；Giovanna, Calandra-Buonaura；Caterina, Tonon；Gianni, Pezzoli；Roberto, Cilia；Mario, Zappia；Alessandra, Nicoletti；Calogero Edoardo, Cicero；Michele, Tinazzi；Pierluigi, Tocco；Nicolò, Cardobi；Aldo, Quattrone

来源：European radiology 2016 年