The Pulmonary Embolism Severity Index (PESI) is a validated prognostic score to estimate the 30-day mortality of emergency department (ED) patients with acute pulmonary embolism (PE). A simplified version (sPESI) was derived but has not been as well studied in the U.S. We sought to validate both indices in a community hospital setting in the U.S. and compare their performance in predicting 30-day all-cause mortality and classification of cases into low-risk and higher-risk categories.This retrospective cohort study included adults with acute objectively confirmed PE from 1/2013 to 4/2015 across 21 community EDs. We evaluated the misclassification rate of the sPESI compared with the PESI. We assessed accuracy of both indices with regard to 30-day mortality.Among 3006 cases of acute PE, the 30-day all-cause mortality rate was 4.4

作者：David R, Vinson；Dustin W, Ballard；Dustin G, Mark；Jie, Huang；Mary E, Reed；Adina S, Rauchwerger；David H, Wang；James S, Lin；Mamata V, Kene；Tamara S, Pleshakov；Dana K, Sax；Jordan M, Sax；D Ian, McLachlan；Cyrus K, Yamin；Clifford J, Swap；Hilary R, Iskin；Ridhima, Vemula；Bethany S, Fleming；Andrew R, Elms；Drahomir, Aujesky

来源：Thrombosis research 2016 年 148卷