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Gestational diabetes mellitus (GDM) is a major pregnancy complication with detrimental effects for both mothers and their children. Accumulating evidence has suggested a potential role for arsenic (As) exposure in the development of GDM, but current studies have not assessed As exposure from water, urine or toenail samples.We investigated the association between As exposure and risk of glucose intolerance and GDM among 1151 women enrolled in the New Hampshire Birth Cohort Study. Arsenic was measured in home well water and via biomarkers (i.e., maternal urine collected ~24-28 weeks gestation and toenail clippings collected 2 weeks postpartum).A total of 105 (9.1 

作者:Shohreh F, Farzan;Anala, Gossai;Yu, Chen;Lisa, Chasan-Taber;Emily, Baker;Margaret, Karagas

来源:Environmental health : a global access science source 2016 年 15卷 1期

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作者:
Shohreh F, Farzan;Anala, Gossai;Yu, Chen;Lisa, Chasan-Taber;Emily, Baker;Margaret, Karagas
来源:
Environmental health : a global access science source 2016 年 15卷 1期
标签:
Arsenic Gestational diabetes Glucose intolerance New Hampshire Pregnancy cohort
Gestational diabetes mellitus (GDM) is a major pregnancy complication with detrimental effects for both mothers and their children. Accumulating evidence has suggested a potential role for arsenic (As) exposure in the development of GDM, but current studies have not assessed As exposure from water, urine or toenail samples.We investigated the association between As exposure and risk of glucose intolerance and GDM among 1151 women enrolled in the New Hampshire Birth Cohort Study. Arsenic was measured in home well water and via biomarkers (i.e., maternal urine collected ~24-28 weeks gestation and toenail clippings collected 2 weeks postpartum).A total of 105 (9.1