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Systemic lupus erythematosus (SLE) is a multifaceted disease, and its diagnosis may be challenging. A blood test for the diagnosis of SLE, the Avise Lupus test, has been recently commercialized and validated in clinical studies.To evaluate the use of the Avise Lupus test by community rheumatologists.The study is a longitudinal, case-control, retrospective review of medical charts. Cases had a positive test result, and controls had a negative result; all patients were anti-nuclear antibodies (ANA) positive but negative for SLE-specific autoantibodies. Features of SLE, diagnosis, and medications at two time points were recorded.Twenty of the 23 cases (87

作者:James, Mossell;John A, Goldman;Derren, Barken;Roberta Vezza, Alexander

来源:The open rheumatology journal 2016 年 10卷

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作者:
James, Mossell;John A, Goldman;Derren, Barken;Roberta Vezza, Alexander
来源:
The open rheumatology journal 2016 年 10卷
标签:
Biomarkers Case-control study Diagnostic test Medical chart review
Systemic lupus erythematosus (SLE) is a multifaceted disease, and its diagnosis may be challenging. A blood test for the diagnosis of SLE, the Avise Lupus test, has been recently commercialized and validated in clinical studies.To evaluate the use of the Avise Lupus test by community rheumatologists.The study is a longitudinal, case-control, retrospective review of medical charts. Cases had a positive test result, and controls had a negative result; all patients were anti-nuclear antibodies (ANA) positive but negative for SLE-specific autoantibodies. Features of SLE, diagnosis, and medications at two time points were recorded.Twenty of the 23 cases (87