Using Systems Genetics to Understanding the Etiology of Complex Disease.-临床诊疗知识库

首页 > Methods in molecular biology (Clifton, N.J.) > Using Systems Genetics to Understanding the Etiology of Complex Disease.

收藏 | 浏览18

Here, we discuss Systems Genetics applications for systematic evaluation of candidate causal genes together with follow-up bioinformatics pathway analysis. The aim of this chapter is to illustrate analytic procedures and we provide examples in the context of Type 1 diabetes (T1day), the risk of which is conferred by over 60 loci. We also describe the Type 1 Diabetes Systems Genetics website and provide a guide for its use and application to other diseases.

作者：Ramesh, Ram；Grant, Morahan

来源：Methods in molecular biology (Clifton, N.J.) 2017 年 1488卷

循证病因

知识库介绍

临床诊疗知识库该平台旨在解决临床医护人员在学习、工作中对医学信息的需求，方便快速、便捷的获取实用的医学信息，辅助临床决策参考。该库包含疾病、药品、检查、指南规范、病例文献及循证文献等多种丰富权威的临床资源。

详细介绍

热门关注

免责声明：本知识库提供的有关内容等信息仅供学习参考，不代替医生的诊断和医嘱。

Using Systems Genetics to Understanding the Etiology of Complex Disease.

| 浏览：18

作者：

Ramesh, Ram；Grant, Morahan

来源：

Methods in molecular biology (Clifton, N.J.) 2017 年 1488卷

标签：

Cis-regulatory genes Nonsynonymous genetic modifiers Trans-regulatory genes Use case Type 1 diabetes Variants that affect gene expression

知识库介绍

详细介绍

临床诊疗知识库现支持机构用户及个人包时用户开通服务。如需开通机构账号，请机构管理员联系我们，联系电话：010-58882667；个人包时开通请直接点击“个人包时订购”，开通后即可使用。