Interval increase in the prevalence of symptomatic cholelithiasis-associated non-alcoholic fatty liver disease over a ten-year period in an Asian population.-临床诊疗知识库

Interval increase in the prevalence of symptomatic cholelithiasis-associated non-alcoholic fatty liver disease over a ten-year period in an Asian population.

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作者：

Kevin Beng Chin, Khaw；Rachel Huiyi, Choi；Juinn Huar, Kam；Bibhas, Chakraborty；Pierce Kah Hoe, Chow

来源：

Singapore medical journal 2016 年

标签：

Asian Singapore cholelithiasis epidemiology non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease (NAFLD) is frequently associated with cholelithiasis. The prevalence of NAFLD has been on the rise in Asia, but the magnitude of this increase has not been previously studied.A retrospective cohort study was carried out on consecutive patients who underwent laparoscopic or open cholecystectomy from November 2001 to November 2004 (cohort 1) and from November 2011 to November 2014 (cohort 2) at Singapore General Hospital. Preoperative diagnostic scans (e.g. ultrasonography, computed tomography and magnetic resonance imaging) and clinical data were reviewed for the presence of fatty liver. Statistical analysis was performed.In cohorts 1 and 2, 127 patients and 99 patients were operated, respectively. Cohort 2 had significantly higher proportions of patients with NAFLD (56.6

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