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To determine the incidence of hepatocellular carcinoma (HCC) and the impact of HCC surveillance on early diagnosis and survival of cirrhotic outpatients.In this retrospective cohort study, cirrhotic outpatients undergoing HCC surveillance between March 2005 and March 2014 were analyzed. Exclusion criteria were HIV coinfection; previous organ transplantation; diagnosis of HCC at first consultation; missing data in the medical chart; and less than 1 year of follow-up. Surveillance was carried out every six months using ultrasound and serum alpha-fetoprotein determination. Ten-year cumulative incidence and survival were estimated through Kaplan-Meier analysis.Four hundred and fifty-three patients were enrolled, of which 57.6

作者:Marcelo Campos, Appel-da-Silva;Suelen Aparecida da Silva, Miozzo;Isabella de Azevedo, Dossin;Cristiane Valle, Tovo;Fernanda, Branco;Angelo Alves, de Mattos

来源:World journal of gastroenterology 2016 年 22卷 46期

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作者:
Marcelo Campos, Appel-da-Silva;Suelen Aparecida da Silva, Miozzo;Isabella de Azevedo, Dossin;Cristiane Valle, Tovo;Fernanda, Branco;Angelo Alves, de Mattos
来源:
World journal of gastroenterology 2016 年 22卷 46期
标签:
Epidemiology Hepatocellular carcinoma Liver cirrhosis Surveillance Survival
To determine the incidence of hepatocellular carcinoma (HCC) and the impact of HCC surveillance on early diagnosis and survival of cirrhotic outpatients.In this retrospective cohort study, cirrhotic outpatients undergoing HCC surveillance between March 2005 and March 2014 were analyzed. Exclusion criteria were HIV coinfection; previous organ transplantation; diagnosis of HCC at first consultation; missing data in the medical chart; and less than 1 year of follow-up. Surveillance was carried out every six months using ultrasound and serum alpha-fetoprotein determination. Ten-year cumulative incidence and survival were estimated through Kaplan-Meier analysis.Four hundred and fifty-three patients were enrolled, of which 57.6