Glutathione S-transferases (GSTs) enzymes are involved in the detoxification of several endogenous and exogenous substances. In this study, we evaluated the effects of two glutathione S-transferase polymorphisms, (GSTM1 and GSTT1) on bipolar disorder (BPD) risk susceptibility in a Tunisian population. These polymorphisms were analyzed in 229 healthy subjects and 109 patients with BPD, using a polymerase chain reaction. Statistical analysis was performed using SPSS 18.0. The relative associations between the GSTs genotypes and BPD were assessed by calculating odds ratios (ORs) and 95

作者：Chahra, Chbili；Ahlem, Elouaer；Neila, Fathallah；Manel, Nouira；Besma Bel Hadj, Jrad；Lotfi, Gaha；Saad, Saguem

来源：Gene 2017 年 607卷