Prognostic Impact of Elective Supraclavicular Nodal Irradiation for Patients with N1 Breast Cancer after Lumpectomy and Anthracycline plus Taxane-based Chemotherapy (KROG 1418): A Multicenter Case-Controlled Study.-临床诊疗知识库

Prognostic Impact of Elective Supraclavicular Nodal Irradiation for Patients with N1 Breast Cancer after Lumpectomy and Anthracycline plus Taxane-based Chemotherapy (KROG 1418): A Multicenter Case-Controlled Study.

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作者：

Haeyoung, Kim；Won, Park；Jeong Il, Yu；Doo Ho, Choi；Seung Jae, Huh；Yeon-Joo, Kim；Eun Sook, Lee；Keun Seok, Lee；Han-Sung, Kang；In Hae, Park；Kyung Hwan, Shin；Chan Woo, Wee；Kyubo, Kim；Kyung Ran, Park；Yong Bae, Kim；Sung Ja, Ahn；Jong Hoon, Lee；Jin Hee, Kim；Mison, Chun；Hyung-Sik, Lee；Jung Soo, Kim；Jihye, Cha

来源：

Cancer research and treatment : official journal of Korean Cancer Association 2017 年

标签：

Adjuvant radiotherapy Breast neoplasms Case-control studies Lymphatic irradiation Taxane

This study was conducted to evaluate the impact of supraclavicular lymph node radiotherapy (SCNRT) on N1 breast cancer patients receiving post-lumpectomy whole-breast irradiation (WBI) and anthracycline plus taxane-based (AT) chemotherapy.We performed a case-control analysis to compare the outcomes of WBI and WBI plus SCNRT (WBI+SCNRT). Among 1,147 patients with N1 breast cancer who received post-lumpectomy radiotherapy and AT-based chemotherapy in 12 hospitals, 542 were selected after propensity score matching. Patterns of failure, disease-free survival (DFS), distant metastasis-free survival (DMFS), and treatment-related toxicity were compared between groups.A total of 41 (7.6

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