To study different imaging criteria for prediction of lymph node metastases (Stage III disease) in colon cancer using CT.In a retrospective setting, 483 consecutive patients with histology proven colon cancer underwent elective primary resection during 2008-2011, a cohort of 119 patients were included. Contrast enhanced CT examinations, in portal-venous phase, were reviewed with assessment of the number of lymph nodes, their anatomical distribution, size, size ratio, internal heterogeneity, presence of irregular outer border and attenuation values. Sensitivity, specificity, PPV and NPV for each studied criteria for prediction of stage III disease was calculated.According to histopathology 80 patients were stage I-II and 39 were stage III. Of the studied CT-criteria for lymph node metastases per patient, internal heterogeneity in at least one lymph node resulted in the best performance with sensitivity, specificity, PPV and NPV of 79, 84, 70 and 89
作者:Erik, Rollvén;Mirna, Abraham-Nordling;Torbj?rn, Holm;Lennart, Blomqvist
来源:Cancer imaging : the official publication of the International Cancer Imaging Society 2017 年 17卷 1期