Fibroblast-growth factor 21 (FGF21) is thought to be important in metabolic regulation. Recently, low protein diets have been shown to increase circulating FGF21 levels. However, when energy contribution from dietary protein is lowered, other macronutrients, such as carbohydrates, must be increased to meet eucaloric balance. This raises the possibility that intake of a diet rich in carbohydrates may induce an increase in plasma FGF21 levels per se. Here we studied the role of dietary carbohydrates on the levels of circulating FGF21 and concomitant physiologic effects by feeding healthy men a carbohydrate rich diet without reducing protein intake.A diet enriched in carbohydrates (80 E

作者：Anne-Marie, Lundsgaard；Andreas M, Fritzen；Kim A, Sj?berg；Lene S, Myrmel；Lise, Madsen；J?rgen F P, Wojtaszewski；Erik A, Richter；Bente, Kiens

来源：Molecular metabolism 2017 年 6卷 1期