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This study focused on quantitative detection of cocaine on Euro banknotes in Germany. A sensitive direct competitive immunoassay was developed and optimized with a limit of detection (LOD) of 5.6ng/L. Exhaustive cocaine extraction by solvent was tested using different methanol concentrations and buffered solutions. Cross-reactivity studies were performed to determine the degree of interference of cocaine metabolites with the immunoassay. Sixty-five Euro banknotes obtained from different districts in Berlin were evaluated. A 100

作者:Nahla A, Abdelshafi;Ulrich, Panne;Rudolf J, Schneider

来源:Talanta 2017 年 165卷

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收藏
| 浏览:43
作者:
Nahla A, Abdelshafi;Ulrich, Panne;Rudolf J, Schneider
来源:
Talanta 2017 年 165卷
标签:
Cocaine Drugs on bills ELISA Enzyme-Linked Immunosorbent Assay Euro banknotes
This study focused on quantitative detection of cocaine on Euro banknotes in Germany. A sensitive direct competitive immunoassay was developed and optimized with a limit of detection (LOD) of 5.6ng/L. Exhaustive cocaine extraction by solvent was tested using different methanol concentrations and buffered solutions. Cross-reactivity studies were performed to determine the degree of interference of cocaine metabolites with the immunoassay. Sixty-five Euro banknotes obtained from different districts in Berlin were evaluated. A 100