To explore feasibility of a randomised study using standardised or individualised multiherb Chinese herbal medicine (CHM) for oligomenorrhoea and amenorrhoea in women with polycystic ovary syndrome (PCOS), to pilot study methods and to obtain clinical data to support sample size calculations.Prospective, pragmatic, randomised feasibility and pilot study with participant and practitioner blinding.2 private herbal practices in the UK.40 women diagnosed with PCOS and oligomenorrhoea or amenorrhoea following Rotterdam criteria.6 months of either standardised CHM or individualised CHM, 16 g daily taken orally as a tea.Our primary objective was to determine whether oligomenorrhoea and amenorrhoea were appropriate as the primary outcome measures for the main study. Estimates of treatment effects were obtained for menstrual rate, body mass index (BMI), weight and hirsutism. Data were collected regarding safety, feasibility and acceptability.Of the 40 participants recruited, 29 (72.5

作者：Lily, Lai；Andrew, Flower；Philip, Prescott；Trevor, Wing；Michael, Moore；George, Lewith

来源：BMJ open 2017 年 7卷 2期