To compare the diagnostic validity of NIA-AA criteria, for AD CSF biomarkers, with our own new criteria.Between 2008 and 2011, 170 patients with Mild Cognitive Impairment (MCI) were included. CSF levels of Aβ1-42, T-tau, P-tau181, and ratios of T-tau/Aβ1-42 and P-tau181/Aβ1-42 were analyzed. In our criteria, we considered 3 or more abnormal variables indicative of a high likelihood of MCI due to AD.After a clinical follow-up of 4.5 ± 1.2 years, 44 patients remained stable, 95 developed AD, 15 other forms of dementia, 7 died and 9 received other diagnoses. Using the NIA-AA criteria and our own criteria, the diagnostic validity of the CSF biomarkers was 58

作者：Maria Empar, Blanco-Cantó；J A, Monge-Argilés；C, Pérez-Cejuela；C, Badía；L, Gabaldón；C, Mu?oz-Ruíz；J, Sánchez-Payá；R, Gasparini-Berenguer；C, Leiva-Santana

来源：American journal of Alzheimer's disease and other dementias 2017 年 32卷 2期