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Crohn's disease is one of the major subtypes of idiopathic inflammatory bowel disease and is characterized by chronic transmural intestinal inflammation of the gastrointestinal tract anywhere from mouth to the anus, with a predilection for the small bowel. Cross-sectional imaging with computed tomography and magnetic resonance enterography plays a key role in confirming diagnosis, identifying and managing complications, assessing disease severity, and identifying response to medical therapy. This review will focus on the role of radiologists in the diagnosis and assessment of Crohn's disease. Additionally, a review of current medical therapy approaches, available medications, and side effects will be discussed. The review will also highlight key complications of medical therapy and associated diseases that should be evaluated by the radiologist with cross-sectional imaging.

作者:Parakkal, Deepak;Sang Hyoung, Park;Eric C, Ehman;Stephanie L, Hansel;Jeff L, Fidler;David H, Bruining;Joel G, Fletcher

来源:Abdominal radiology (New York) 2017 年 42卷 4期

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作者:
Parakkal, Deepak;Sang Hyoung, Park;Eric C, Ehman;Stephanie L, Hansel;Jeff L, Fidler;David H, Bruining;Joel G, Fletcher
来源:
Abdominal radiology (New York) 2017 年 42卷 4期
标签:
Computed Crohn’s disease management Magnetic resonance imaging Tomography Tumor necrosis factor-alpha/antagonists and inhibitors X-ray
Crohn's disease is one of the major subtypes of idiopathic inflammatory bowel disease and is characterized by chronic transmural intestinal inflammation of the gastrointestinal tract anywhere from mouth to the anus, with a predilection for the small bowel. Cross-sectional imaging with computed tomography and magnetic resonance enterography plays a key role in confirming diagnosis, identifying and managing complications, assessing disease severity, and identifying response to medical therapy. This review will focus on the role of radiologists in the diagnosis and assessment of Crohn's disease. Additionally, a review of current medical therapy approaches, available medications, and side effects will be discussed. The review will also highlight key complications of medical therapy and associated diseases that should be evaluated by the radiologist with cross-sectional imaging.