Screening for Down syndrome (DS) is a key component of antenatal care, recommended to be universally offered to women irrespective of age or background. Despite this, the diagnosis of DS is often not made until the neonatal period.To retrospectively describe and compare the differences in populations with an antenatal diagnosis (AD) and neonatal diagnosis (ND) of DS and to explore why an antenatal diagnosis was not made.The cohorts were women cared for at Westmead Hospital whose pregnancy received a diagnosis of DS between 2006 and 2015. The demographic variables of the AD and ND cohorts were examined and reasons why an antenatal diagnosis was not made in the ND cohort were analysed.There were 127 diagnoses of DS in the 10-year period, of which 41

作者：Rebecca M, Moses；James H W, Brown；Dale C, Wright；Hayley, Diplock；Sarah J, Melov；Therese Mary, McGee

来源：The Australian & New Zealand journal of obstetrics & gynaecology 2017 年 57卷 2期