To assess the impact of baseline characteristics on clinical outcomes in the LixiLan-L trial, a randomized open-label trial designed to evaluate the efficacy and safety of iGlarLixi, a novel fixed-ratio combination of insulin glargine 100 U (iGlar) plus lixisenatide, in comparison with iGlar over 30 weeks in a population of patients with type 2 diabetes mellitus (T2DM) inadequately controlled on a previous regimen of basal insulin alone or in combination with 1 or 2 oral glucose-lowering drugs.In this exploratory analysis of LixiLan-L (N = 736), efficacy outcomes were assessed within population subgroups derived from the following baseline characteristics: glycated haemoglobin [HbA1c; <8
作者:Carol, Wysham;Riccardo C, Bonadonna;Vanita R, Aroda;Manuel, Puig Domingo;Christoph, Kapitza;William, Stager;Christine, Yu;Elisabeth, Niemoeller;Elisabeth, Souhami;Richard M, Bergenstal
来源:Diabetes, obesity & metabolism 2017 年