Accurate evaluation of distribution of disease and response to systemic anti-cancer therapy (SACT) is important in the optimal management of metastatic breast cancer. Whole-body magnetic resonance imaging (WB-MRI) has increased accuracy over computerised tomography of the chest, abdomen and pelvis (CT-CAP) for detecting liver and bone disease, but its effect on patient management is largely unexplored. This study investigates the effects of using WB-MRI alongside CT-CAP on SACT decisions in standard clinical practice for patients with metastatic breast cancer.Metastatic breast cancer patients who had undergone WB-MRI within 14 d of CT-CAP were studied. Data on distribution and extent of disease and SACT response assessment from original WB-MRI and CT-CAP reports were compared. Contemporaneous medical records provided data on therapy decisions at each time point.Analyses were performed on 210 pairs of WB-MRI and CT-CAP in 101 patients. In 53.3

作者：Michael, Kosmin；Andreas, Makris；Priya V, Joshi；Mei-Lin, Ah-See；David, Woolf；Anwar R, Padhani

来源：European journal of cancer (Oxford, England : 1990) 2017 年 77卷