The recently developed total cerebral small-vessel disease (CSVD) score might appropriately reflect the total burden or severity of CSVD. We investigated whether the total CSVD score is associated with long-term outcomes during follow-up in patients with acute ischemic stroke.In total, 1,096 consecutive patients with acute ischemic stroke who underwent brain magnetic resonance imaging were enrolled. We calculated the total CSVD score for each patient after determining the burden of cerebral microbleeds (CMBs), high-grade white-matter hyperintensities (HWHs), high-grade perivascular spaces (HPVSs), and asymptomatic lacunar infarctions (ALIs). We recorded the date and cause of death for all of the patients using data from the Korean National Statistical Office. We compared the long-term mortality rate with the total CSVD score using Cox proportional-hazards models.CMBs were found in 26.8

作者：Tae Jin, Song；Jinkwon, Kim；Dongbeom, Song；Joonsang, Yoo；Hye Sun, Lee；Yong Jae, Kim；Hyo Suk, Nam；Ji Hoe, Heo；Young Dae, Kim

来源：Journal of clinical neurology (Seoul, Korea) 2017 年 13卷 2期