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The aim of the study was to analyze the effect of conventional glucose management, which aimed to maintain glucose levels <155 mg/dL (8.5 mmol/L), on glucose control and the outcomes of patients with acute ischaemic stroke (IS) in a clinical practice setting.This was a multicenter, prospective cohort study of patients with acute IS. Patients were classified into four groups based on their initial 48-h capillary glucose levels and the administration of and response to corrective treatment: (i) untreated and maximum glucose levels <155 mg/dL (8.5 mmol/L) within the first 48 h; (ii) treated and good responders [glucose levels persistently <155 mg/dL (8.5 mmol/L)]; (iii) treated and non-responders [any glucose values ≥155 mg/dL (8.5 mmol/L) during the 24 h after the start of corrective treatment]; and (iv) untreated with any glucose value ≥155 mg/dL (8.5 mmol/L). The primary outcome was death or dependence at 3 months (blinded rater).A total of 213 patients were included. Ninety-seven (45.5

作者:B, Fuentes;B E, Sanz-Cuesta;M, Gutiérrez-Fernández;P, Martínez-Sánchez;A, Lisbona;R, Madero-Jarabo;R, Delgado-Mederos;J, Gállego-Cullere;M, Rodríguez-Yá?ez;M, Martínez-Zabaleta;M, Freijo;M, Alonso de Leci?ana;J C, Portilla;A, Gil-Nú?ez;E, Díez-Tejedor

来源:European journal of neurology 2017 年 24卷 9期

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作者:
B, Fuentes;B E, Sanz-Cuesta;M, Gutiérrez-Fernández;P, Martínez-Sánchez;A, Lisbona;R, Madero-Jarabo;R, Delgado-Mederos;J, Gállego-Cullere;M, Rodríguez-Yá?ez;M, Martínez-Zabaleta;M, Freijo;M, Alonso de Leci?ana;J C, Portilla;A, Gil-Nú?ez;E, Díez-Tejedor
来源:
European journal of neurology 2017 年 24卷 9期
标签:
acute ischaemic stroke hyperglycemia insulin outcome
The aim of the study was to analyze the effect of conventional glucose management, which aimed to maintain glucose levels <155 mg/dL (8.5 mmol/L), on glucose control and the outcomes of patients with acute ischaemic stroke (IS) in a clinical practice setting.This was a multicenter, prospective cohort study of patients with acute IS. Patients were classified into four groups based on their initial 48-h capillary glucose levels and the administration of and response to corrective treatment: (i) untreated and maximum glucose levels <155 mg/dL (8.5 mmol/L) within the first 48 h; (ii) treated and good responders [glucose levels persistently <155 mg/dL (8.5 mmol/L)]; (iii) treated and non-responders [any glucose values ≥155 mg/dL (8.5 mmol/L) during the 24 h after the start of corrective treatment]; and (iv) untreated with any glucose value ≥155 mg/dL (8.5 mmol/L). The primary outcome was death or dependence at 3 months (blinded rater).A total of 213 patients were included. Ninety-seven (45.5