Lung cancer prognosis is related to various factors; however, the comprehensive relationship between these factors, including microRNAs (miRNAs), and lung cancer prognosis has not been determined. Thus, the aim of this study was to identify the key factors associated with lung cancer prognosis.We retrospectively analyzed prognosis and relevant factors in 216 non-small cell lung cancer (NSCLC) patients diagnosed from January 2008 to December 2014. Paraffin-embedded lung tissue samples were used to detect miRNA-21 and miRNA-155. Clinical information was collected, including tumor malignancy, tumor node metastasis (TNM) classification, pathological type, site of the original tumor, and lung involvement. The association between factors and overall survival was analyzed. A Cox proportional hazard model was used to perform univariate and multivariate analyses.Age at surgery (hazard ratio [HR] 1.021, 95

作者：Xin, Wang；Yi, Zhang；Xiuyi, Zhi

来源：Thoracic cancer 2017 年